Most of the Nobel prizewinners in science won the award for a specific discovery, a research breakthrough. Warshel, Levitt and their third partner Martin Karplus won the Nobel for creating a totally new field of research. They developed computerized models for the understanding of complex biological systems, or to quote the prize committee from Sweden, they brought the cyber world into the experimental lab. Their journey began at the end of the 1960’s with the computer "Golem 2" at the Weizmann Institute, and ended with the ability to accurately describe the movements and responses of molecules within a living cell.

This is also the story of Arieh Warshel, originally a member of a kibbutz and a breakthrough scientist who was rejected by the Israeli scientific community and was forced to uproot to America. Now, after winning, he is square off with the Israeli academic establishment which turned its back on him.